Publications
2021
- Du Bruyn E, Fukutani KF, Rockwood NS, Schutz C, Meintjes GA, Arriaga MB, Cubillos-Angulo JM, Tibúrcio R, Sher AF, Riou C, Wilkinson KA, Andrade BB, Wilkinson RJ:
Inflammatory profile of patients with tuberculosis with or without HIV-1 co-infection: a prospective cohort study and immunological network analysis
The Lancet Microbe Volume 2, Issue 8, E375-E385, 10.1016/S2666-5247(21)00037-9 - Chen RY, Yu X, Smith B, Liu X, Gao J, Diacon AH, Dawson R, Tameris M, Zhu H, Qu Y, Zhang R, Pan S, Jin X, Goldfeder LC, Cai Y, Arora K, Wang J, Vincent J, Malherbe ST, Thienemann F, Wilkinson RJ, Walzl G, Barry III CE:
Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis
The Lancet Microbe Volume 2, Issue 10, E518-E526, 10.1016/S2666-5247(21)00058-6
2020
- Riou C, Du Bruyn E, Ruzive S, Goliath RT, Lindestam Arlehamn CS, Sette A, Sher A, Barber DL, Wilkinson RJ:
Disease extent and anti-tubercular treatment response correlates with Mycobacterium tuberculosis-specific CD4 T cell phenotype regardless of HIV-1 status
Clinical and Translational Immunology Volume 9, Issue 9, e1176, 10.1002/cti2.1176 - Schutz C, Chirehwa M, Barr D, Ward A, Janssen S, Burton R, Wilkinson RJ, Shey M, Wiesner L, Denti P, McIlleron H, Maartens G, Meintjes G:
Early antituberculosis drug exposure in hospitalized patients with human immunodeficiency virus‐associated tuberculosis
British Journal of Clinical Pharmacology Volume 86, Issue 5, 7 January, 10.1111/bcp.14207 - Lubbers R, Sutherland JS, Goletti D, de Paus RA, Dijkstra DJ, van Moorsel CHM, Veltkamp M, Vestjens SMT, Bos WJW, Petrone L, Malherbe ST, Walzl G, Gelderman KA, Groeneveld GH, Geluk A, Ottenhoff THM, Joosten SA, Trouw LA.:
Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients
Molecular Immunology Volume 120, April, 187-195, 10.1016/j.molimm.2020.02.006 - Eribo OA, Leqheka MS, Malherbe ST, McAnda S, Stanley K, van der Spuy GD, Walzl G, Chegou NN:
Host urine immunological biomarkers as potential candidates for the diagnosis of tuberculosis
International Journal of Infectious Diseases Volume 99, October, 473-481, 10.1016/j.ijid.2020.08.019 - Malherbe ST, Chen RY, Dupont P, Kant I, Kriel M, Loxton AG, Smith B, Beltran CGG, van Zyl S, McAnda S, Abrahams C, Maasdorp E, Doruyter A, Via LE, Barry CE 3rd, Alland D, Richards SG, Ellman A, Peppard T, Belisle J, Tromp G, Ronacher K, Warwick JM, Winter J, Walzl G.:
Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response
EJNMMI Research 10 February, 10.1186/s13550-020-0591-9 - Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, Vogl T, Walzl G, du Plessis N, Kaushal D, Scriba T, Zuñiga J, Khader S.:
S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis
The Journal of Clinical Investigation 5 March, 10.1172/JCI130546
2019
- Darboe F, Mbandi SK, Naidoo K, Yende-Zuma N, Lewis L, Thompson EG, Duffy FJ, Fisher M, Filander E, van Rooyen M, Bilek N, Mabwe S, McKinnon LR, Chegou N, Loxton A, Walzl G, Tromp G, Padayatchi N, Govender D, Hatherill M, Karim SA, Zak DE, Penn-Nicholson A, Scriba TJ and the SATVI Clinical Immunology Team:
Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy
Frontiers in Microbiology 26 June, 10.3389/fmicb.2019.01441 - Ronacher K, Chegou NN, Kleynhans L, Djoba Siawaya JF, du Plessis N, Loxton AG, Maasdorp E, Tromp G, Kidd M, Stanley K, Kriel M, Menezes A, Gutschmidt A, van der Spuy GD, Warren RM, Dietze R, Okwera A, Thiel B, Belisle JT, Cliff JM, Boom WH, Johnson JL, van Helden PD, Dockrell HM, Walzl G.:
Distinct serum biosignatures are associated with different tuberculosis treatment outcomes
Tuberculosis Volume 118, September - Geluk, G. Walzl, T. Ottenhoff, P. Corstjens:
Het humane afweersysteem als basis voor snelle tbc-diagnostiek met de Multi-Biomarker Test
Tegen de Tuberculose, 115 :1 10-11 - Naomi F Walker, Charles Opondo, Graeme Meintjes, Nishtha Jhilmeet, Jon S Friedland, Paul T Elkington, Robert J Wilkinson, Katalin A Wilkinson:
Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus–associated Tuberculosis
Clinical Infectious Diseases Volume 70, Issue 9, 1 May 2020, 1865–1874, 10.1093/cid/ciz501 - Cerrone, M., Bracchi, M., Wasserman, S., Pozniak, A., Meintjes, G., Cohen, K., Wilkinson, R.J.:
Safety implications of combined antiretroviral and anti-tuberculosis drugs
Expert Opinion On Drug Safety Volume 19 - Issue 1, 10.1080/14740338.2020.1694901 - Cari Stek, Brian Allwood, Elsa Du Bruyn, Jozefien Buyze, Charlotte Schutz, Friedrich Thienemann, Adele Lombard, Robert J. Wilkinson, Graeme Meintjes, Lutgarde Lynen:
The effect of HIV-associated tuberculosis, tuberculosis-IRIS, and prednisone on lung function
European Respiratory Journal Vol 55 Issue 6, 10.1183/13993003.01692-2019 - Mmamapudi Kubjane, Natacha Berkowitz, Rene Goliath, Naomi S Levitt, Robert J Wilkinson, Tolu Oni:
Tuberculosis, Human Immunodeficiency Virus, and the Association With Transient Hyperglycemia in Periurban South Africa
Clinical Infectious Diseases 26 September, 10.1093/cid/ciz928
2018
- Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry III, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl, James M. Warwick & the Catalysis Biomarker Consortium:
A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images
EJNMMI Research 25 June, 10.1186/s13550-018-0411-7 - Warsinske HC, Rao AM, Moreira FMF, Santos PCP, Liu AB, Scott M, Malherbe ST, Ronacher K, Walzl G, Winter J, Sweeney TE, Croda J, Andrews JR, Khatri P.:
Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response
JAMA Network Open 26 October, 10.1001/jamanetworkopen.2018.3779 - Charlotte Schutz, Angharad G Davis, Bianca Sossen, Rachel P-J Lai, Mpiko Ntsekhe, Yolande XR Harley & Robert J Wilkinson:
Corticosteroids as an adjunct to tuberculosis therapy
Expert Review of Respiratory Medicine Volume 12, 2018 - Issue 10, 23 Aug, 10.1080/17476348.2018.1515628 - Cari Stek, Brian Allwood, Naomi F. Walker, Robert J. Wilkinson, Lutgarde Lynen and Graeme Meintjes.:
The Immune Mechanisms of Lung Parenchymal Damage in Tuberculosis and the Role of Host-Directed Therapy
Frontiers in Microbiology 30 October 2018, 10.3389/fmicb.2018.02603
2017
- Chen, R.Y., Via, L.E., Dodd, L.E., Walzl, G., Malherbe, S.T., Loxton, A.G., Dawson, R., Wilkinson, R.J., Thienemann, F., Tameris, M., Hatherill, M., Diacon, A., Liu, X., Xing, J., Jin, X., Ma, Z., pan, S., Zhang, G., Gao, Q., Jiang, Q., Zhu, H., Liang, L:
Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial
Gates Open Research 1:9, 6 November 2017, 10.12688/gatesopenres.12750.1)